产品
编 号：F132725
分子式：C13H12ClNOS2
分子量：297.82
分子式：C13H12ClNOS2
分子量：297.82
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
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10mg
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询价
结构图
CAS No: 135330-08-4
产品详情
生物活性：
RP-54745 is an inhibitor of macrophage stimulation and interleukin-1 production, and a potential antirheumatic compound.
体内研究：
RP-54745 (5 mg/kg) is effective at moderating oral doses in different mouse models of induced arthritis and in the MRL/lpr mice, genetically predisposed to develop an autoimmune pathology including arthritic disorders. The clinical status of the MRL mice, and several of their disturbed biochemical and immunological parameters, improved after a 3-month treatment with RP-54745.
体外研究：
RP-54745 diminishes LPS-induced interleukin-1 (IL-1) production by murine peritoneal macrophages.
RP-54745 is an inhibitor of macrophage stimulation and interleukin-1 production, and a potential antirheumatic compound.
体内研究：
RP-54745 (5 mg/kg) is effective at moderating oral doses in different mouse models of induced arthritis and in the MRL/lpr mice, genetically predisposed to develop an autoimmune pathology including arthritic disorders. The clinical status of the MRL mice, and several of their disturbed biochemical and immunological parameters, improved after a 3-month treatment with RP-54745.
体外研究：
RP-54745 diminishes LPS-induced interleukin-1 (IL-1) production by murine peritoneal macrophages.
产品资料
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