产品
编 号:F132309
分子式:C19H15F4N5O2
分子量:421.35
产品类型
结构图
CAS No: 1352416-78-4
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产品详情
生物活性:
BACE1-IN-2 is a 1,4-Oxazine β-Secretase 1 (BACE1) inhibitor with an IC50 of 22 nM.
体外研究:
BACE1-IN-2 (Compound 3) is 10-fold more potent toward BACE1 than BACE2, inhibition of which may lead to hair depigmentation. BACE1-IN-2 inhibits hAβ42 cell with an IC50 of 6.0 nM.