产品
编 号:F131279
分子式:C27H36N2O4
分子量:452.59
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10mM*1mL in DMSO
询价
询价
50mg
572
In-stock
100mg
958
In-stock
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生物活性:
Repaglinide is an insulin secretagogue for the treatment of type-2 diabetes mellitus.

体内研究:
Repaglinide (AG-EE 623ZW) is very rapidly absorbed (tmax less than 1 hour) with a t1/2 of less than one hour. Furthermore, Repaglinide is inactivated in the liver and more than 90 % excreted via the bile. Repaglinide (1 mg/kg p.o.) is effective (P<0.001) as an insulin-releasing agent in a rat model (low-dose streptozotocin) of type 2 diabetes.

体外研究:
Repaglinide reduces postprandial glucose levels by enhancing the early phase of insulin secretion and increasing the total amount of insulin secreted.
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