产品
编 号：F130807
分子式：C14H19NO2
分子量：233.31
分子式：C14H19NO2
分子量：233.31
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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50mg
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结构图
CAS No: 134865-70-6
产品详情
生物活性：
8-M-PDOT (AH-002) is a selective melatonin MT2 receptor agonist. 8-M-PDOT is 5.2-fold selective for MT2 over MT1 receptors. 8-M-PDOT binds human recombinant MT2 and MT2 receptors with pKi values of 8.23 and 8.95 respectively. 8-M-PDOT has anxiolytic-like activity.
体内研究：
8-M-PDOT (10 μg/μL; administrated into the dorsal striatum by bilateral cannulas; for 30 minutes; male Wistar rats) treatment shows anxiolytic-like effect.Animal Model:Male Wistar rats (280-320 g) with Rotenone
Dosage:10 μg/μL
Administration:Administrated into the dorsal striatum by bilateral cannulas; for 30 minutes
Result:Increased percentage of time spent in the open arms and in the number of open arms entries.
8-M-PDOT (AH-002) is a selective melatonin MT2 receptor agonist. 8-M-PDOT is 5.2-fold selective for MT2 over MT1 receptors. 8-M-PDOT binds human recombinant MT2 and MT2 receptors with pKi values of 8.23 and 8.95 respectively. 8-M-PDOT has anxiolytic-like activity.
体内研究：
8-M-PDOT (10 μg/μL; administrated into the dorsal striatum by bilateral cannulas; for 30 minutes; male Wistar rats) treatment shows anxiolytic-like effect.Animal Model:Male Wistar rats (280-320 g) with Rotenone
Dosage:10 μg/μL
Administration:Administrated into the dorsal striatum by bilateral cannulas; for 30 minutes
Result:Increased percentage of time spent in the open arms and in the number of open arms entries.
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