产品
编 号：F130574
分子式：C17H12FN3O2S
分子量：341.36
分子式：C17H12FN3O2S
分子量：341.36
产品类型
规格
价格
是否有货
1mg
询价
询价
结构图
CAS No: 134729-13-8
产品详情
生物活性：
COX-2-IN-2 is a selective and inducible COX2 inhibitor with an IC50 of 0.24 μM. COX-2-IN-1 is an anti-inflammatory compound with anti-inflammatory and analgesic activities.
体内研究：
COX-2-IN-2 has oral ED50 values of 0.030 and 0.47mg/kg on adjuvant-induced arthritis and collagen-induced arthritis, respectively, and an ED30 value of 7.4mg/kg in the yeast-induced hyperalgesia (Randall-Selitto) assay. COX-2-IN-2 shows good analgesic activity and no ulcerogenicity.
体外研究：
COX-2-IN-2 shows no COX-1 inhibition even at 100μM.
COX-2-IN-2 is a selective and inducible COX2 inhibitor with an IC50 of 0.24 μM. COX-2-IN-1 is an anti-inflammatory compound with anti-inflammatory and analgesic activities.
体内研究：
COX-2-IN-2 has oral ED50 values of 0.030 and 0.47mg/kg on adjuvant-induced arthritis and collagen-induced arthritis, respectively, and an ED30 value of 7.4mg/kg in the yeast-induced hyperalgesia (Randall-Selitto) assay. COX-2-IN-2 shows good analgesic activity and no ulcerogenicity.
体外研究：
COX-2-IN-2 shows no COX-1 inhibition even at 100μM.
产品资料
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