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编 号:F014722
分子式:C12H6Cl2N2O6
分子量:345.09
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10mM*1mL in DMSO
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5mg
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10mg
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25mg
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50mg
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100mg
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生物活性:
Niclofolan (BAY 9015) is an orally active anthelmintic agent. Niclofolan can be used in the research of parasite infection.

体内研究:
Niclofolan (2 mg/kg, intramuscular injection) is effective against fasciola hepatica infected sheep.Niclofolan (1 or 2 mg/kg, oral gavage ) shows therapeutic effects against P.iloktsuenesis infected rats.Animal Model:fasciola hepatica infected sheep
Dosage:2 mg/kg
Administration:Intramuscular injection
Result:Showed effectiveness against the infection and produced no untoward effects except for transient signs of pain at the site of injection.
Animal Model:Rats infected with P.iloktsuenesis
Dosage:1 mg/kg, daily for 3 days; 2 mg/kg every other day for 2 times.
Administration:Oral gavage
Result:Reduced the worms in rats.

体外研究:
Niclofolan (0.12 mg/mL, 60 min) is effective against Gyrodactylus sp. under in vitro conditions.
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