产品
编 号：F128820
分子式：C12H17NO
分子量：191.27
分子式：C12H17NO
分子量：191.27
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
500mg
320
In-stock
1g
400
In-stock
结构图
CAS No: 134-62-3
产品详情
生物活性：
Diethyltoluamide (DEET) is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects. Diethyltoluamide is toxic to hepatocytes and can lead to many physiological, pharmacological, and behavioral abnormalities, particularly motor deficits and learning and memory dysfunction.
体内研究：
Diethyltoluamide (40 mg/kg，直接应用于皮肤，每周 7 天，共 60 天) 导致大鼠大脑皮质和海马中弥漫性神经元细胞死亡和细胞骨架异常，以及小脑中的浦肯野神经元丢失。
体外研究：
Diethyltoluamide (25-250 μM, 24-72h) 对 HepG2 细胞具有毒性。
Diethyltoluamide (DEET) is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects. Diethyltoluamide is toxic to hepatocytes and can lead to many physiological, pharmacological, and behavioral abnormalities, particularly motor deficits and learning and memory dysfunction.
体内研究：
Diethyltoluamide (40 mg/kg，直接应用于皮肤，每周 7 天，共 60 天) 导致大鼠大脑皮质和海马中弥漫性神经元细胞死亡和细胞骨架异常，以及小脑中的浦肯野神经元丢失。
体外研究：
Diethyltoluamide (25-250 μM, 24-72h) 对 HepG2 细胞具有毒性。
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