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编 号:F128710
分子式:C14H22N4O9
分子量:390.35
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生物活性:
α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors.

体外研究:
α2β1 Integrin Ligand Peptide (DGEA) (0.015-2.0 mM) inhibits SA11, RRV, and Wa infection in a dose-dependent manner and had no effect on CRW-8 infectivity.α2β1 Integrin Ligand Peptide induces tyrosine kinase-dependent calcium mobilization in osteoblasts and fibroblasts at concentrations of ≥0.5 mM.α2β1 Integrin Ligand Peptide loses its ability to inhibit SA11 binding at 1.0 mM.
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