产品
编 号:F126195
分子式:C19H18Cl2N3NaO6S
分子量:510.32
产品类型
结构图
CAS No: 13412-64-1
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产品详情
生物活性:
Dicloxacillin Sodium hydrate (Dicloxacillin sodium salt monohydrate) is a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used to treat infections caused by susceptible Gram-positive bacteria, active against beta-lactamase-producing organisms such as Staphylococcus aureus.
体内研究:
Dicloxacillin exhibits therapeutic activity in murine peritonitis-sepsis model and all the mice are survivied.Animal Model:Female outbred Swiss Webster mice (Murine peritonitis-sepsis model).
Dosage:125 mg/kg.
Administration:IV injection, single doses.
Result:All the mice survived.
体外研究:
Dicloxacillin exhibits EC50 values of 0.06 and 0.50 mg/L in ATCC 25923 and E19977, respectively. Dicloxacillin exhibits MIC values of 0.125 and 0.5 mg/L in ATCC 25923 and E19977 with pH 7.4, respectively.