产品
编 号:F125926
分子式:C23H16F7N5O2
分子量:527.39
产品类型
结构图
CAS No: 1340593-59-0
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产品详情
生物活性:
Oteseconazole (VT-1161) is a potent and orally active anti-fungal agent. Oteseconazole potently binds to and inhibits Candida albicans cytochrome P45051 (CYP51) activity (Kd ≤39 nM), shows no obvious effect on human CYP51. Oteseconazole also can be used for the research of dermatophytes.
体内研究:
Oteseconazole (5-25 mg/kg, 口服, 每日一次, 9 天) 可有效抑制须癣毛癣菌 (T. mentagrophytes) 感染的豚鼠的真菌生长并改善感染的临床症状。