产品
编 号：F125736
分子式：C6H7NaO6
分子量：198.11
分子式：C6H7NaO6
分子量：198.11
产品类型
规格
价格
是否有货
500mg
320
In-stock
1g
400
In-stock
结构图
CAS No: 134-03-2
产品详情
生物活性：
L-Ascorbic acid sodium salt (Sodium ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid sodium salt selectively inhibits Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid sodium salt is also a collagen deposition enhancer and an elastogenesis inhibitor.
体内研究：
Tg rats treated with L-Ascorbic acid sodium salt (Sodium?L-ascorbate) show a higher incidence of carcinoma (29.6%), compared to those without L-Ascorbic acid sodium salt (15.4%). Independent of the L-Ascorbic acid sodium salt treatment, transgenic rats exhibit various kinds of malignant tumors in various organs. After 12 weeks of PEITC-treatment, both simple hyperplasia and papillary or nodular (PN) hyperplasia have developed in all animals, but the majority of these lesions have disappeared at week 48, irrespective of the L-Ascorbic acid sodium salt-treatment. The same lesions after 24 weeks of PEITC-treatment have progressed to dysplasia and carcinoma, in a small number of cases by week 48, but enhancement by the L-Ascorbic acid sodium salt-treatment is evident only with simple hyperplasias and PN hyperplasias in rats.
体外研究：
The conditioned?medium?for?B16F10?cells significantly inhibits?cell?apoptosis?induced by?L-Ascorbic acid sodium salt (Sodium?L-ascorbate) (10 mM), and the effective ingredients in the?medium?show a relative molecular mass below 5,000.
L-Ascorbic acid sodium salt (Sodium ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid sodium salt selectively inhibits Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid sodium salt is also a collagen deposition enhancer and an elastogenesis inhibitor.
体内研究：
Tg rats treated with L-Ascorbic acid sodium salt (Sodium?L-ascorbate) show a higher incidence of carcinoma (29.6%), compared to those without L-Ascorbic acid sodium salt (15.4%). Independent of the L-Ascorbic acid sodium salt treatment, transgenic rats exhibit various kinds of malignant tumors in various organs. After 12 weeks of PEITC-treatment, both simple hyperplasia and papillary or nodular (PN) hyperplasia have developed in all animals, but the majority of these lesions have disappeared at week 48, irrespective of the L-Ascorbic acid sodium salt-treatment. The same lesions after 24 weeks of PEITC-treatment have progressed to dysplasia and carcinoma, in a small number of cases by week 48, but enhancement by the L-Ascorbic acid sodium salt-treatment is evident only with simple hyperplasias and PN hyperplasias in rats.
体外研究：
The conditioned?medium?for?B16F10?cells significantly inhibits?cell?apoptosis?induced by?L-Ascorbic acid sodium salt (Sodium?L-ascorbate) (10 mM), and the effective ingredients in the?medium?show a relative molecular mass below 5,000.
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