产品
编 号：F124255
分子式：C22H18O4
分子量：346.38
分子式：C22H18O4
分子量：346.38
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结构图
CAS No: 133740-30-4
产品详情
生物活性：
BChE-IN-11 (compound 10) is a potent, selective and non-competitive BChE (butyrylcholinesterase) inhibitor, with an IC50 of 2.1 μM. BChE-IN-11 can be used for Alzheimer's disease (AD) research.
体外研究：
BChE-IN-11 (compound 10) shows inhibition activity for BChE and AChE, with inhibition of 96.6 ± 1.2% and 19.1 ± 3.8% at 25 μg/mL, respectively.BChE-IN-11 binds to the active pocket of BChE via multiple hydrogen bonds with His438, Pro285, Gly115 and π–π stacking with Tyr332 and Trp82.
BChE-IN-11 (compound 10) is a potent, selective and non-competitive BChE (butyrylcholinesterase) inhibitor, with an IC50 of 2.1 μM. BChE-IN-11 can be used for Alzheimer's disease (AD) research.
体外研究：
BChE-IN-11 (compound 10) shows inhibition activity for BChE and AChE, with inhibition of 96.6 ± 1.2% and 19.1 ± 3.8% at 25 μg/mL, respectively.BChE-IN-11 binds to the active pocket of BChE via multiple hydrogen bonds with His438, Pro285, Gly115 and π–π stacking with Tyr332 and Trp82.
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