产品
编 号:F123699
分子式:C29H32N6OS
分子量:512.67
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10mM*1mL in DMSO
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5mg
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10mg
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25mg
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50mg
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生物活性:
PF-5190457 (PF-05190457) is a potent and selective ghrelin receptor inverse agonist with a pKi of 8.36.

体内研究:
PF-5190457 has excellent selectivity and demonstrates robust increases in glucose-stimulated insulin secretion in human whole and dispersed islets.

体外研究:
PF-5190457 has a superior balance of ghrelin receptor pharmacology and off-target selectivity.
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