产品
编 号：F123624
分子式：C25H31NO6
分子量：441.52
分子式：C25H31NO6
分子量：441.52
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
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询价
10mg
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25mg
询价
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50mg
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100mg
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结构图
CAS No: 1334526-14-5
产品详情
生物活性：
(±)-ML 209 (compound 4n), a diphenylpropanamide, is a retinoic acid-related orphan receptor RORγ antagonist with an IC50 of 1.1 μM. (±)-ML 209 inhibits RORγt transcriptional activity with an IC50 of 300 nM in HEK293t cells. (±)-ML 209 inhibits the transcriptional activity of RORγt, but not RORα in cells. (±)-ML 209 selectively inhibits murine Th17 cell differentiation without affecting the differentiation of na?ve CD4+ T cells into other lineages, including Th1 and regulatory T cells.
(±)-ML 209 (compound 4n), a diphenylpropanamide, is a retinoic acid-related orphan receptor RORγ antagonist with an IC50 of 1.1 μM. (±)-ML 209 inhibits RORγt transcriptional activity with an IC50 of 300 nM in HEK293t cells. (±)-ML 209 inhibits the transcriptional activity of RORγt, but not RORα in cells. (±)-ML 209 selectively inhibits murine Th17 cell differentiation without affecting the differentiation of na?ve CD4+ T cells into other lineages, including Th1 and regulatory T cells.
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