产品
编 号：F123086
分子式：C25H39N3O5
分子量：461.59
分子式：C25H39N3O5
分子量：461.59
产品类型
规格
价格
是否有货
1mg
询价
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5mg
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10mg
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50mg
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结构图
CAS No: 133407-86-0
产品详情
生物活性：
MG-115 is a potent and reversible proteasome inhibitor, with Kis of 21 nM and 35 nM for 20S and 26S proteasome, respectively. MG-115 specifically inhibit the chymotrypsin-like activity of the proteasome, induces p53-dependent apoptosis.
体外研究：
MG-115 (0.1-10 μM; 24 h) dose-dependently decreases the viability of HepG2 cells.MG-115 (0.1-10 μM; 24 h) amplifies the reporter gene expression mediated by CWK18 DNA condensates.
MG-115 is a potent and reversible proteasome inhibitor, with Kis of 21 nM and 35 nM for 20S and 26S proteasome, respectively. MG-115 specifically inhibit the chymotrypsin-like activity of the proteasome, induces p53-dependent apoptosis.
体外研究：
MG-115 (0.1-10 μM; 24 h) dose-dependently decreases the viability of HepG2 cells.MG-115 (0.1-10 μM; 24 h) amplifies the reporter gene expression mediated by CWK18 DNA condensates.
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