产品
编 号:F120363
分子式:C713C6H8Cl2N2O4
分子量:333.08
产品类型
结构图
CAS No: 1325808-64-7
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产品详情
生物活性:
Niclosamide-13C6 is the 13C6 labeled Niclosamide. Niclosamide (BAY2353)?is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibits STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.
体外研究:
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.