产品
编 号：F120269
分子式：C11H11O4P
分子量：238.18
分子式：C11H11O4P
分子量：238.18
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结构图
CAS No: 132541-52-7
产品详情
生物活性：
HNMPA is a membrane impermeable insulin receptor tyrosine kinase inhibitor. HNMPA inhibits serine and tyrosine autophosphorylation by the human insulin receptor. HNMPA has no effect on protein kinase C or cyclic AMP-dependent protein kinase activities
体外研究：
HNMPA inhibits the phosphorylation of a synthetic peptide substrate composed of insulin receptor residues 1290-1319 on serines-1305/1306 by partially purified insulin receptors.HNMPA blocks GABA-dependent insulin inhibition, and reduces neuronal firing after GABA application.
HNMPA is a membrane impermeable insulin receptor tyrosine kinase inhibitor. HNMPA inhibits serine and tyrosine autophosphorylation by the human insulin receptor. HNMPA has no effect on protein kinase C or cyclic AMP-dependent protein kinase activities
体外研究：
HNMPA inhibits the phosphorylation of a synthetic peptide substrate composed of insulin receptor residues 1290-1319 on serines-1305/1306 by partially purified insulin receptors.HNMPA blocks GABA-dependent insulin inhibition, and reduces neuronal firing after GABA application.
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