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编 号：F119599
分子式：C27H32O8
分子量：484.54
分子式：C27H32O8
分子量：484.54
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CAS No: 132196-54-4
产品详情
生物活性：
Chrodrimanin B, a metabolite of a fungal, is a potent, non-open-channel-blocking antagonist on?B.?mori GABAR RDL with an IC50?of 1.13 nM. Chrodrimanin B attenuates the peak current amplitude of the GABA response of RDL with an IC50?of 1.66 nM.?Chrodrimanin B, a meroterpenoid, shows insecticidal activity.
体外研究：
Chrodrimanin B exhibits much weaker blocking action on human α1β2γ2 GABAR compared to RDL (IC50=1.48 μM). Chrodrimanin B shows competitive actions at low concentrations and non-competitive actions at higher concentrations on?B.?mori GABAR RDL.
Chrodrimanin B, a metabolite of a fungal, is a potent, non-open-channel-blocking antagonist on?B.?mori GABAR RDL with an IC50?of 1.13 nM. Chrodrimanin B attenuates the peak current amplitude of the GABA response of RDL with an IC50?of 1.66 nM.?Chrodrimanin B, a meroterpenoid, shows insecticidal activity.
体外研究：
Chrodrimanin B exhibits much weaker blocking action on human α1β2γ2 GABAR compared to RDL (IC50=1.48 μM). Chrodrimanin B shows competitive actions at low concentrations and non-competitive actions at higher concentrations on?B.?mori GABAR RDL.
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