产品
编 号：F119571
分子式：C19H24ClNO
分子量：317.85
分子式：C19H24ClNO
分子量：317.85
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1g
询价
询价
结构图
CAS No: 132-18-3
产品详情
生物活性：
Diphenylpyraline hydrochloride is a potent histamine H1?receptor antagonist. Diphenylpyraline hydrochloride acts as an orally active antihistamine agent?with antimuscarinic and antiallergic effects. Diphenylpyraline hydrochloride can be used for the relief of allergic conditions including rhinitis and hay fever, and in pruritic skin disorders in vivo.
体内研究：
Diphenylpyraline hydrochloride (intraperitoneal?injection; 5-10 mg/kg) elevates extracellular dopamine levels (~200%) in mouse nucleus accumbens and induces locomotor activation in mice.Animal Model:C57BL/6 mice
Dosage:5-10 mg/kg
Administration:Intraperitoneal?injection
Result:Had psychostimulant properties.
体外研究：
Diphenylpyraline hydrochloride (10 μM) markedly inhibits dopamine uptakein mouse nucleus accumbens slices.
Diphenylpyraline hydrochloride is a potent histamine H1?receptor antagonist. Diphenylpyraline hydrochloride acts as an orally active antihistamine agent?with antimuscarinic and antiallergic effects. Diphenylpyraline hydrochloride can be used for the relief of allergic conditions including rhinitis and hay fever, and in pruritic skin disorders in vivo.
体内研究：
Diphenylpyraline hydrochloride (intraperitoneal?injection; 5-10 mg/kg) elevates extracellular dopamine levels (~200%) in mouse nucleus accumbens and induces locomotor activation in mice.Animal Model:C57BL/6 mice
Dosage:5-10 mg/kg
Administration:Intraperitoneal?injection
Result:Had psychostimulant properties.
体外研究：
Diphenylpyraline hydrochloride (10 μM) markedly inhibits dopamine uptakein mouse nucleus accumbens slices.
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