产品
编 号：F118782
分子式：C22H26BrClN2O3S
分子量：513.88
分子式：C22H26BrClN2O3S
分子量：513.88
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
325
In-stock
10mg
520
In-stock
50mg
1840
In-stock
100mg
3200
In-stock
结构图
CAS No: 131707-23-8
产品详情
生物活性：
Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells. Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity.
体内研究：
Umifenovir (45-180 mg/kg; p.o.; daily for 5 days) suppresses the transcription of influenza viruses (IFV) -associated inflammatory cytokines.Animal Model:BALB/c mice were infected with A/FM/1/47 (H1N1)
Dosage:45, 90, and 180 mg/kg
Administration:p.o.; daily for 5 days
Result:Decreased the transcription of cytokines in murine lung following the IFV A (H1N1) Infection.
体外研究：
Umifenovir hydrochloride exhibits a wide range and potent antiviral activity against a number of viruses including influenza A, B and C viruses, respiratory syncytial virus, adenovirus, parainfluenza type 5 and rhinovirus type 14, avian coronavirus, infectious bronchitis virus and Marek disease virus, hepatitis B virus and hepatitis C virus.
Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells. Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity.
体内研究：
Umifenovir (45-180 mg/kg; p.o.; daily for 5 days) suppresses the transcription of influenza viruses (IFV) -associated inflammatory cytokines.Animal Model:BALB/c mice were infected with A/FM/1/47 (H1N1)
Dosage:45, 90, and 180 mg/kg
Administration:p.o.; daily for 5 days
Result:Decreased the transcription of cytokines in murine lung following the IFV A (H1N1) Infection.
体外研究：
Umifenovir hydrochloride exhibits a wide range and potent antiviral activity against a number of viruses including influenza A, B and C viruses, respiratory syncytial virus, adenovirus, parainfluenza type 5 and rhinovirus type 14, avian coronavirus, infectious bronchitis virus and Marek disease virus, hepatitis B virus and hepatitis C virus.
产品资料
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