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编 号:F118168
分子式:C29H31F3N6O2
分子量:552.59
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10mM*1mL in DMSO
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5mg
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10mg
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50mg
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生物活性:
TAK1/MAP4K2 inhibitor 1 is a potent dual TGFβ-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2) inhibitor, with IC50s of 41.1 nM and 18.2 nM, respectively.

体内研究:
TAK1/MAP4K2 inhibitor 1 has moderate terminal elimination half-life (t1/2=2.94 h for mice (1 mg/kg, iv)).
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