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编 号:F117637
分子式:C116H170N30O40S
分子量:2656.83
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生物活性:
Neuropeptide Y (1-24) (human) is a neuropeptide with potencies in inhibiting the electricity stimulated twitch response of rat vas deferens. Neuropeptide Y (1-24) (human) stimulates N-methyl-D-aspartate (NMDA)-induced neuronal activation in the rat CA3 region of the dorsal hippocampus in vivo.

体外研究:
Neuropeptide Y (1-24) (human) dose-dependently enhances N-methyl-D-aspartate (NMDA)-induced activation of CA3 dorsal hippocampus pyramidal neurons.Neuropeptide Y (1-24) (human) selectively increases the amplitude of the twitch response to electrical stimulation at low micromolar concentrations but shows no affinity toward [3H]NPY brain receptor sites and no inhibition of the twitch response in the rat vas deferens preparation at concentrations up to 1.0 mM.
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