产品
编 号:F116025
分子式:C13H10O5
分子量:246.22
产品类型
结构图
CAS No: 131-12-4
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产品详情
生物活性:
Pimpinellin is a constituent of Cyrtomium fortumei (J.). Pimpinellin inhibits the growth of tumor cells via the induction of tumor cell apoptosis.
体外研究:
Pimpinellin has potent cytotoxic activities against the three tumor cells MGC-803, PC3, and A375, with the IC50 values of 14.4±0.3?μM, 20.4±0.5?μM, and 29.2±0.6?μM, respectively. Pimpinellin inhibits the growth of MGC-803 cells via the induction of tumor cell apoptosis, with apoptosis ratio of 27.44% after 72?h of treatment at 20?μM.