产品
编 号：F115878
分子式：C10H9N3OS
分子量：219.26
分子式：C10H9N3OS
分子量：219.26
产品类型
规格
价格
是否有货
25mg
询价
询价
50mg
询价
询价
结构图
CAS No: 1310744-67-2
产品详情
生物活性：
PFM39, a Mirin analog, is a potent and selective MRE11 exonuclease inhibitor. PFM39 inhibits phosphate rotation for dsDNA exonuclease activity. PFM39 does not inhibit TmMre11 or human MRE11/MRN endonuclease activity.
体外研究：
PFM39 (100 μM) treatment impairs G2-phase double-strand break (DSB) repair in 1BR3-hTERT fibrolasts following ionizing irradiation (IR). PFM39 (50 μM) inhibits homologous recombination (HR) without significantly increasing NHEJ.
PFM39, a Mirin analog, is a potent and selective MRE11 exonuclease inhibitor. PFM39 inhibits phosphate rotation for dsDNA exonuclease activity. PFM39 does not inhibit TmMre11 or human MRE11/MRN endonuclease activity.
体外研究：
PFM39 (100 μM) treatment impairs G2-phase double-strand break (DSB) repair in 1BR3-hTERT fibrolasts following ionizing irradiation (IR). PFM39 (50 μM) inhibits homologous recombination (HR) without significantly increasing NHEJ.
产品资料
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