产品
编 号:F112243
分子式:C10H22Cl2N2O4Pt
分子量:500.28
产品类型
结构图
CAS No: 129580-63-8
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产品详情
生物活性:
Satraplatin is an alkylating agent, with potent antitumor effect.
体外研究:
Satraplatin needs to avoid light in the solution, and it is unstable in the alkaline state but stable in the acidic state.Satraplatin has potent antitumor activity. Satraplatin combined with dichloroacetate (DCA) inhibits UMC-11 cells with an IC50 of 1.36 ± 0.11 μM. Satraplatin also suppresses CDDP-resistant (KB-R) cells (IC50, 7.04 μM), and causes G2/M arrest in KB-R cells.