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编 号:F112216
分子式:C25H34F3N7O
分子量:505.58
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生物活性:
AKT-IN-2 is a potent, selective and orally bioavailable AKT inhibitor with an IC50 of 5 nM for AKT1.

体外研究:
AKT-IN-2 (Compound 8) also inhibits P70S6K, PKA, PKCβ2, RSK1, and pGSK3β with IC50s of 0.399, 0.084, 3.98, 0.568, and 0.092 μM, respectively.
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