产品
编 号:F112187
分子式:C172H263N43O52
分子量:3765.25
产品类型
结构图
CAS No: 1295353-98-8
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生物活性:
Apraglutide (FE 203799), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum.
体内研究:
Apraglutide (FE 203799; 5 mg/kg/dose, subcutaneously, twice on days 0 and 4 postsurgery) treated piglets are healthy, have significant lower fecal fat and energy losses and exhibite intestinal lengthening, greater small-intestinal weight, longer villus height, and greater crypt depth on day 7.Animal Model:NewbornDuroc piglets, 2–5 days old and weighing between 2-2.6 kg.
Dosage:5 mg/kg/dose.
Administration:Subcutaneously, twice on days 0 and 4 postsurgery.
Result:On day 7, treated piglets were healthy, had significant lower fecal fat and energy losses and exhibited intestinal lengthening, greater small-intestinal weight, longer villus height, and greater crypt depth.