产品
编 号：F112160
分子式：C63H88N2O14
分子量：1097.38
分子式：C63H88N2O14
分子量：1097.38
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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5mg
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10mg
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50mg
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100mg
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200mg
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结构图
CAS No: 129496-10-2
产品详情
生物活性：
Milbemycin oxime is an orally active macrolide with broad-spectrum antiparasitic activity. Milbemycin oxime is a mixture of oximes consisting of oxime derivatives corresponding to milbemycin A4 and A3. Milbemycin oxime binds to glutamate-gated chloride channels and has inhibitory potency against intestinal nematodes and lung/heart worms.
体内研究：
Milbemycin oxime (0.5 mg/kg，口服) 和 Afoxolaner (2.5 mg/kg，口服) 可预防犬的血管圆线虫感染。Animal Model:Angiostrongylus vasorum infected dogs
Dosage:0.5 g, 1 g, and 2 g containing 9.375 mg?+?1.875 mg, 18.75 mg?+?3.75 mg, and 37.5 mg?+?7.5 mg .
Administration:p.o., on study days 0, 28, 56 and 84 with a combination of Afoxolaner plus Milbemycin oxime chewable tablets.
Result:Reduced the geometric mean worm count and geometric mean faecal larval counts in the treated group.
Milbemycin oxime is an orally active macrolide with broad-spectrum antiparasitic activity. Milbemycin oxime is a mixture of oximes consisting of oxime derivatives corresponding to milbemycin A4 and A3. Milbemycin oxime binds to glutamate-gated chloride channels and has inhibitory potency against intestinal nematodes and lung/heart worms.
体内研究：
Milbemycin oxime (0.5 mg/kg，口服) 和 Afoxolaner (2.5 mg/kg，口服) 可预防犬的血管圆线虫感染。Animal Model:Angiostrongylus vasorum infected dogs
Dosage:0.5 g, 1 g, and 2 g containing 9.375 mg?+?1.875 mg, 18.75 mg?+?3.75 mg, and 37.5 mg?+?7.5 mg .
Administration:p.o., on study days 0, 28, 56 and 84 with a combination of Afoxolaner plus Milbemycin oxime chewable tablets.
Result:Reduced the geometric mean worm count and geometric mean faecal larval counts in the treated group.
产品资料
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