产品
编 号：F111372
分子式：C21H21N
分子量：287.4
分子式：C21H21N
分子量：287.4
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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5mg
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10mg
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25mg
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50mg
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100mg
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结构图
CAS No: 129-03-3
产品详情
生物活性：
Cyproheptadine is a potent and orally active 5-HT2A receptor antagonist, with antidepressant and antiserotonergic effects. Cyproheptadine has antiplatelet and thromboprotective activities. Cyproheptadine can be used for the research of thromboembolic disorders.
体内研究：
Cyproheptadine 可用于动物建模，构建糖尿病模型。Animal Model:C57BL/6 mice (8-10 weeks old)
Dosage:1 mg/kg
Administration:Intraperitoneal injection; daily, for 5 days
Result:Prolonged occlusion times and tail bleeding times in mice.
体外研究：
Cyproheptadine (0.01-100 nM; 1 minute) dose-dependently inhibits serotonin-enhanced ADP-induced mouse platelet aggregation in vitro.Cyproheptadine (10 nM) has the ability to inhibit 15 μM serotonin-enhanced ADP-induced (1 μM) tyrosine phosphorylation in platelets in vitro.Cyproheptadine inhibits human platelet PS exposure (Annexin V), P-selectin, and GPIIb-IIIa (PAC-1 binding) activation in vitro.
Cyproheptadine is a potent and orally active 5-HT2A receptor antagonist, with antidepressant and antiserotonergic effects. Cyproheptadine has antiplatelet and thromboprotective activities. Cyproheptadine can be used for the research of thromboembolic disorders.
体内研究：
Cyproheptadine 可用于动物建模，构建糖尿病模型。Animal Model:C57BL/6 mice (8-10 weeks old)
Dosage:1 mg/kg
Administration:Intraperitoneal injection; daily, for 5 days
Result:Prolonged occlusion times and tail bleeding times in mice.
体外研究：
Cyproheptadine (0.01-100 nM; 1 minute) dose-dependently inhibits serotonin-enhanced ADP-induced mouse platelet aggregation in vitro.Cyproheptadine (10 nM) has the ability to inhibit 15 μM serotonin-enhanced ADP-induced (1 μM) tyrosine phosphorylation in platelets in vitro.Cyproheptadine inhibits human platelet PS exposure (Annexin V), P-selectin, and GPIIb-IIIa (PAC-1 binding) activation in vitro.
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