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编 号:F107018
分子式:C24H28N4O4
分子量:436.5
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10mM*1mL in DMSO
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5mg
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10mg
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25mg
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50mg
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生物活性:
Chroman 1 is a highly potent and selective ROCK inhibitor. Chroman 1 is more potent against ROCK2 (IC50=1 pM) than ROCK1 (IC50=52 pM). Chroman 1 also has inhibitory activity against MRCK, with an IC50 of 150 nM.

体外研究:
Chroman 1 (50 nM,24 小时) 抑制 caspase-3/7 激活并减少人多能干细胞的凋亡。
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