产品
编 号:F107018
分子式:C24H28N4O4
分子量:436.5
产品类型
结构图
CAS No: 1273579-40-0
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产品详情
生物活性:
Chroman 1 is a highly potent and selective ROCK inhibitor. Chroman 1 is more potent against ROCK2 (IC50=1 pM) than ROCK1 (IC50=52 pM). Chroman 1 also has inhibitory activity against MRCK, with an IC50 of 150 nM.
体外研究:
Chroman 1 (50 nM,24 小时) 抑制 caspase-3/7 激活并减少人多能干细胞的凋亡。