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编 号:F106868
分子式:C20H24FN3O4
分子量:389.42
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100mg
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500mg
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生物活性:
Balofloxacin (Q-35) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin can be used for the research of respiratory, intestinal, and urinary tract infections.

体内研究:
Balofloxacin (200 mg/kg/day; p.o. for 5 d) reduces the counts of viable M. pneumonia in the lungs of hamsters.Balofloxacin eye drops (0.5%) is effective in S. aureus bacterial keratitis of rabbits.

体外研究:
Balofloxacin (25 mg/mL; 1 h) decreases the growth of S. aureus that adhered to human corneal epithelial cells (HCECs).Balofloxacin inhibits the S. aureus ATCC 25923, with a MIC of 0.125 mg/mL.Balofloxacin (0.05-500 μg/mL; 72 h) does not induce toxicity on the HCECs at a low concentration, such as 0.625 mg/mL.
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