产品
编 号：F013021
分子式：C25H27ClN6O4S
分子量：543.04
分子式：C25H27ClN6O4S
分子量：543.04
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CAS No: 1027513-54-7
产品详情
生物活性：
PSB-0788 is a new selective high-affinity A2B antagonist with IC50 value of 3.64 nM and Ki value of 0.393 nM, respeactively. PSB-0788 can be used for the research for chronic inflammatory lung diseases.
体外研究：
PSB-0788 (compound 17) has high potency at the A2BAdoR with IC50 value of 3.64 nM.PSB-0788 has good profile of affinity and selectivity (Ki: 0.393 nM (A2B human recombinant); >1000 nM (A3 human recombinant); 333 nM (A2A human recombinant); 1730 nM (A2A rat brain striatal membranes);2240 nM (A1 human recombinant); 386 nM (A1 rat brain cortical membranes)).
PSB-0788 is a new selective high-affinity A2B antagonist with IC50 value of 3.64 nM and Ki value of 0.393 nM, respeactively. PSB-0788 can be used for the research for chronic inflammatory lung diseases.
体外研究：
PSB-0788 (compound 17) has high potency at the A2BAdoR with IC50 value of 3.64 nM.PSB-0788 has good profile of affinity and selectivity (Ki: 0.393 nM (A2B human recombinant); >1000 nM (A3 human recombinant); 333 nM (A2A human recombinant); 1730 nM (A2A rat brain striatal membranes);2240 nM (A1 human recombinant); 386 nM (A1 rat brain cortical membranes)).
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