产品
编 号:F098081
分子式:C14H13NO5
分子量:275.26
产品类型
结构图
CAS No: 125697-93-0
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产品详情
生物活性:
Lavendustin C is a potent Ca2+ calmodulin-dependent kinase II (CaMK II) inhibitor with an IC50 of 0.2 μM. Lavendustin C inhibits EGFR-associated tyrosine kinase (IC50=0.012 μM) and pp60c-src(+) kinase (IC50=0.5 μM) .
体外研究:
Lavendustin C (Compound 5) shows potent inhibitory activity, and it may be the core structure responsible for inhibition of tyrosine kinase. Lavendustin C (10-150 μM) inhibits tyrosine kinase-associated neutrophil degranulation and superoxide generation.