产品
编 号：F096591
分子式：C30H34N2O6
分子量：518.6
分子式：C30H34N2O6
分子量：518.6
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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结构图
CAS No: 1255303-54-8
产品详情
生物活性：
JTE-952 is a potent, oral active and selective Type II inhibitor of colony stimulating factor-1 receptor (CSF-1R or cFMS, type III receptor tyrosine kinase), with IC50 values of 13 nM and 261 nM for CSF1R and TrkA , respectively. Effective against a mouse collagen-induced model of arthritis.
体内研究：
JTE-952 (3 mg/kg, p.o. once-daily) treatment reduces the overall progression of the clinical score, including inflammation and bone erosion in mouse model of collagen-induced arthritis (CIA model).Animal Model:Mouse model of collagen-induced arthritis (CIA model).
Dosage:3 mg/kg.
Administration:Oral once-daily.
Result:Reduced the overall progression of the clinical score, including inflammation and bone erosion.
JTE-952 is a potent, oral active and selective Type II inhibitor of colony stimulating factor-1 receptor (CSF-1R or cFMS, type III receptor tyrosine kinase), with IC50 values of 13 nM and 261 nM for CSF1R and TrkA , respectively. Effective against a mouse collagen-induced model of arthritis.
体内研究：
JTE-952 (3 mg/kg, p.o. once-daily) treatment reduces the overall progression of the clinical score, including inflammation and bone erosion in mouse model of collagen-induced arthritis (CIA model).Animal Model:Mouse model of collagen-induced arthritis (CIA model).
Dosage:3 mg/kg.
Administration:Oral once-daily.
Result:Reduced the overall progression of the clinical score, including inflammation and bone erosion.
产品资料
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