产品
编 号:F096194
分子式:C25H26N4O5
分子量:462.5
产品类型
结构图
CAS No: 1254035-84-1
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产品详情
生物活性:
AZD1979 is a Melanin-concentrating hormone receptor 1 (MCHr1) antagonist with an IC50 of ~12 nM.
体内研究:
In DIO mice, initial AZD1979-mediate body weight loss is driven by decreasing food intake, but an additional component of preserving energy expenditure is apparent in pair-feeding and indirect calorimetry studies. AZD1979 also dose-dependently reduces body weight in dogs.