产品
编 号：F089688
分子式：C110H214N6O39P2
分子量：2306.84
分子式：C110H214N6O39P2
分子量：2306.84
产品类型
规格
价格
是否有货
1mg
询价
询价
结构图
CAS No: 1246298-62-3
产品详情
生物活性：
Kdo2-Lipid A ammonium is a chemically defined lipopolysaccharide (LPS) with endotoxin activity equal to LPS. Kdo2-Lipid A ammonium is highly selective for TLR4. Kdo2-Lipid A ammonium stimulates the release of both TNF and PGE2.
体内研究：
KDO2-Lipid A (i.t.) activates toll-like receptor 4 (TLR4) in rats.Animal Model:Rats (Male Holzman Sprague-Dawley, 300–400 g)
Dosage:0.1 to 10 μg
Administration:I.T.; 0.1-10 μg; prior and 15, 30, 60, 90 and 120 min after injection of Kdo2-Lipid A.
Result:Intrathecal injection of 1 μg Kdo2-Lipid A induces allodynia, and the animals appeared to be sick after i.t. injection of Kdo2-Lipid A.
体外研究：
Kdo2-Lipid A (1 μM) stimulates the release of both TNF and PGE2 from the adult rat spinal astrocytes cell cultures.
Kdo2-Lipid A ammonium is a chemically defined lipopolysaccharide (LPS) with endotoxin activity equal to LPS. Kdo2-Lipid A ammonium is highly selective for TLR4. Kdo2-Lipid A ammonium stimulates the release of both TNF and PGE2.
体内研究：
KDO2-Lipid A (i.t.) activates toll-like receptor 4 (TLR4) in rats.Animal Model:Rats (Male Holzman Sprague-Dawley, 300–400 g)
Dosage:0.1 to 10 μg
Administration:I.T.; 0.1-10 μg; prior and 15, 30, 60, 90 and 120 min after injection of Kdo2-Lipid A.
Result:Intrathecal injection of 1 μg Kdo2-Lipid A induces allodynia, and the animals appeared to be sick after i.t. injection of Kdo2-Lipid A.
体外研究：
Kdo2-Lipid A (1 μM) stimulates the release of both TNF and PGE2 from the adult rat spinal astrocytes cell cultures.
产品资料
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