产品
编 号:F087959
分子式:C20H14F4N4O2S
分子量:450.41
产品类型
结构图
CAS No: 1242137-16-1
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产品详情
生物活性:
N-desmethyl Enzalutamide is the active metabolite of Enzalutamide.N-desmethyl Enzalutamide is the active metabolite of Enzalutamide. N-desmethyl Enzalutamide demonstrates primary and secondary pharmacodynamics of similar potency to Enzalutamide and circulates at approximately the same plasma concentrations as enzalutamide.
体内研究:
N-desmethyl Enzalutamide 是一种活性代谢物,被认为有助于恩杂鲁胺的临床效果,因为它显示出与恩杂鲁胺相似效力的主要和次要药效学并且在与恩杂鲁胺大致相同的血浆浓度下循环。羧酸代谢物在药理上无活性,循环血浆浓度比恩杂鲁胺低约 25%。