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编 号:F086031
分子式:C8H20NO4P
分子量:225.22
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1mg
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5mg
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10mg
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25mg
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50mg
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100mg
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生物活性:
CGP 35348?is a selective, brain penetrant, centrally active GABAB receptor antagonist with an EC50 of 34 μM.?CGP 35348 shows affinity for the GABAB receptor only. CGP 35348 has a potential to improve neuromuscular coordination and spatial learning in albino mouse following neonatal brain damage.

体内研究:
CGP 35348 可增强非 REM 睡眠和快速眼动 (REM) 睡眠并减少强烈的尖波放电。Animal Model:Eight male Wistar rats
Dosage:100, 300, and 900 mg/kg?
Administration:Intraperitoneally given
Result:Produced an increase in the duration of REM sleep compared to the saline-injected control group at 100 and 300 mg/kg.
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