产品
编 号:F456400
分子式:CuSO4·5H2O
分子量:249.69
产品类型
结构图
CAS No: 7758-99-8
联系客服
产品详情
生物活性:
Copper sulfate pentahydrate, 99% is a biochemical reagent. Copper sulfate pentahydrate, 99% reduces the production of ROS and the expression levels of MyD88 as well as c-Rel genes. Copper sulfate pentahydrate, 99% decreases the activities of T-SOD, CAT, and GSH, increases the activities of caspase-3, caspase-8, and caspase-9. Copper sulfate pentahydrate, 99% is cytotoxic to various cells. Copper sulfate pentahydrate, 99% has antioxidant activity. Copper sulfate pentahydrate, 99% can be used in the research of diabetes, Parkinson's disease and DMBA (HY-W011845)-induced tumors.
体内活性:
Copper sulfate (20-25 μg/0.2 mL;隔日服用,连续服用 30 天) pentahydrate, 99% 可预防糖尿病,并维持 STZ (HY-13753) 诱导的糖尿病 C57BL6 雌性小鼠的胰腺 β 细胞功能。
Copper sulfate (2.5 mg/kg;腹腔注射;在 MPP+ 前 16/24 h 服用) pentahydrate, 99% 可阻断 MPP+ 诱导的小鼠纹状体脂质过氧化和多巴胺耗竭。
Copper sulfate (饮用水中约含 50 mg Cu2+/L) pentahydrate, 99% 可延缓 DMBA (HY-W011845) 诱导的 C57BL/6J 雌性小鼠卵巢颗粒细胞肿瘤的发展小鼠。
体外活性:
Copper sulfate pentahydrate (6.25-200 mg/mL; 24 h), 99% 显著降低三种人肠上皮细胞系 (HCT116、HT-29 和 SW480) 的细胞活力。
Copper sulfate (2.4 mg Cu/L; 24 h) pentahydrate, 99% 显著降低斜带石斑鱼 (Epinephelus coioides) 原代肝细胞的活力。
Copper sulfate (5-100 µM) pentahydrate, 99% 对 CHO 细胞生长或抗体产生没有影响,但导致培养物活力出现轻微的剂量依赖性下降。