产品
编 号:F380377
分子式:C15H11ClO6
分子量:322.7
产品类型
10mM * 1mL in DMSO
660
In-stock
结构图
CAS No: 528-58-5
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产品详情
生物活性:
Cyanidin Chloride (IdB 1027), a subclass of anthocyanin, displays antioxidant and anti-carcinogenesis properties. Cyanidin Chloride (IdB 1027) inhibits osteoclast formation, hydroxyapatite resorption, and receptor activator of NF-κB ligand (RANKL)-induced osteoclast marker gene expression.
体内活性:
Cyanidin Chloride (IdB 1027) protects against OVX-induced bone loss in OVX-induced osteoporosis mouse model.
体外活性:
Cyanidin Chloride (IdB 1027) inhibits receptor activator of NF-κB ligand (RANKL)-induced NF-κB activation, suppresses the degradation of IκB-α and attenuates the phosphorylation of extracellular signal-regulated kinases (ERK). Cyanidin Chloride (IdB 1027) abrogates RANKL-induced calcium oscillations, the activation of nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1), and the expression of c-Fos.