产品
编 号:F085807
分子式:C18H27N3O6S3
分子量:477.62
产品类型
结构图
CAS No: 1236208-20-0
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生物活性:
Leucomethylene blue (TRx0237) mesylate, an orally active second-generation tau protein aggregation inhibitor (Ki of 0.12 μM), could be used for the study of Alzheimer's Disease. Leucomethylene blue mesylate is a common reduced form of Methylene Blue, Methylene Blue is a member of the thiazine class of dyes.
体外研究:
Leucomethylene blue (100 nM,48 h) mesylate 不仅降低了 tau 和 p-tau 的表达水平,而且逆转了 Aβ25-35 对食欲素 A 和腺苷 A1R 表达水平的促进作用。