产品
编 号:F085635
分子式:C17H21F3O3
分子量:330.34
产品类型
结构图
CAS No: 123557-91-5
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产品详情
生物活性:
rac-BHFF is a potent and orally active allosteric enhancer of GABAB receptor.
体内研究:
rac-BHFF has anxiolytic-like properties in stress-induced hyperthermia (SIH) in mice.rac-BHFF (3, 10, 30 and 100?mg/kg, p.o.) reverses SIH and high significance was reached for 100?mg?kg?1 (P<0.001).Animal Model:Male NMRI mice (20-25?g).
Dosage:3, 10, 30 or 100?mg/kg.
Administration:P.O..
Result:Significantly increased the LRR effects of a subthreshold dose of baclofen at doses of 3?mg/kg and above.