产品
编 号：F763024
分子式：C24H22N4O4
分子量：430.46
分子式：C24H22N4O4
分子量：430.46
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 3031536-71-4
产品详情
生物活性：
PRMT5:MEP50 PPI is a novel PRMT5:MEP50 protein-protein interaction (PRMT5:MEP50 PPI) inhibitor, shows anti-tumor activity and anti-proliferative activity of lung and prostate cancer cells.
体外研究：
PRMT5:MEP50 PPI (0-10 μM; 72 h) inhibits the growth of prostate cancer cells.PRMT5:MEP50 PPI (250-1000 nM; 72 h) decreases the expression of global arginine 3 residue of histone H4 (H4R3me2s) level in prostate cancer cells.PRMT5:MEP50 PPI (500 nM; 72 h) de-represseses the PRMT5: MEP50-regulated IVL gene of prostate cancer cells.PRMT5:MEP50 PPI treatment inhibits multiple PRMT5-regulated pathways critical to the survival and proliferation of lung and prostate cancer cells.
PRMT5:MEP50 PPI is a novel PRMT5:MEP50 protein-protein interaction (PRMT5:MEP50 PPI) inhibitor, shows anti-tumor activity and anti-proliferative activity of lung and prostate cancer cells.
体外研究：
PRMT5:MEP50 PPI (0-10 μM; 72 h) inhibits the growth of prostate cancer cells.PRMT5:MEP50 PPI (250-1000 nM; 72 h) decreases the expression of global arginine 3 residue of histone H4 (H4R3me2s) level in prostate cancer cells.PRMT5:MEP50 PPI (500 nM; 72 h) de-represseses the PRMT5: MEP50-regulated IVL gene of prostate cancer cells.PRMT5:MEP50 PPI treatment inhibits multiple PRMT5-regulated pathways critical to the survival and proliferation of lung and prostate cancer cells.
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