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编 号:F763007
分子式:C61H93N5O9S
分子量:1072.48
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生物活性:
PROTAC Hemagglutinin Degrader-1 (Compound V3) is a potent PROTAC influenza hemagglutinin (HA) degrader with a median degradation concentration of 1.44 μM. PROTAC Hemagglutinin Degrader-1 shows broad-spectrum anti-influenza virus activity.

体内研究:
PROTAC Hemagglutinin Degrader-1 (0-20 mg/kg; i.v.; daily for 5 days) protects mice against influenza A virus-induced toxic effects.PROTAC Hemagglutinin Degrader-1 displays a moderate oral bioavailability of approximately 6.8%.
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