产品
编 号：F762993
分子式：C20H22N4O
分子量：334.41
分子式：C20H22N4O
分子量：334.41
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CAS No: 3032200-62-4
产品详情
生物活性：
FAK-IN-4 (Compound 7d) is potential FAK inhibitor with anticancer activities. FAK-IN-4 induces cell apoptosis.
体外研究：
FAK-IN-4 (Compound 7d) (0-200 μM, 72 h) shows antiproliferative activity against triple-negative breast cancer (TNBC) cells.FAK-IN-4 (0-20 μM, 24 h) inhibits cell invasion and migration of MDA-MB-231 cells.FAK-IN-4 (0-20 μM, 72 h) causes dose-dependent Y925 dephosphorylation of FAK, and induces apoptosis in MDA-MB-231 cells.FAK-IN-4 inhibits the formation of focal adhesions (FAs) and stress fibers (SFs) in MDA-MB-231 cells.
FAK-IN-4 (Compound 7d) is potential FAK inhibitor with anticancer activities. FAK-IN-4 induces cell apoptosis.
体外研究：
FAK-IN-4 (Compound 7d) (0-200 μM, 72 h) shows antiproliferative activity against triple-negative breast cancer (TNBC) cells.FAK-IN-4 (0-20 μM, 24 h) inhibits cell invasion and migration of MDA-MB-231 cells.FAK-IN-4 (0-20 μM, 72 h) causes dose-dependent Y925 dephosphorylation of FAK, and induces apoptosis in MDA-MB-231 cells.FAK-IN-4 inhibits the formation of focal adhesions (FAs) and stress fibers (SFs) in MDA-MB-231 cells.
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