产品
编 号:F762961
分子式:C25H33NO5
分子量:427.53
产品类型
结构图
CAS No: 3030588-01-0
联系客服
产品详情
生物活性:
NVS-STG2 is a molecular glue that targets STING and activates STING-mediated immune signaling. NVS-STG2 induces higher-order oligomerization of human STING by binding to pockets between adjacent STING dimer transmembrane domains, effectively acting as a molecular glue. NVS-STGI enhances the activity of cGAMP by inducing the formation of more abundant and larger oligomers. NVS-STG2 produces antitumor activity in animal models.