产品
编 号:F762956
分子式:C24H17F3N4O3
分子量:466.41
产品类型
结构图
CAS No: 3026111-73-6
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产品详情
生物活性:
TrkA-IN-3 is a potent, subselective and allosteric TrkA inhibitor, with an IC50 of 22.4 nM. TrkA-IN-3 shows more than 8000-fold selectivity for TrkA over TrkB and TrkC. TrkA-IN-3 can be used for the research of pain.
体外研究:
TrkA-IN-3 (compound 5) demonstrates 73.9% and 64.8% of kinase inhibition towards TrkA at concentrations of 1 μM and 0.1 μM , respectively.