产品
编 号:F762934
分子式:C54H63N7O11
分子量:986.12
产品类型
结构图
CAS No: 3023438-19-6
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产品详情
生物活性:
CypD-IN-4 is a potent and subtype-selective cyclophilin D (CypD) inhibitor. CypD-IN-4 has CypD affinity with an IC50 value of 0.057 μM. CypD-IN-4 can be used for the research of several diseases including oxidative stress, neurodegenerative disorders, liver diseases, aging, autophagy and diabetes.
体外研究:
CypD-IN-4 (B53) has selectivity for inhibiting CypD, CypA, CypB and CypE with IC50 values of 0.057 μM, 3.4 μM, 1.1 μM and 0.8 μM, respectively.CypD-IN-4 (20 μM) inhibits mitochondrial permeability transition pore opening in isolated mitochondria.