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编 号:F762917
分子式:C18H19F2N5O
分子量:359.37
产品类型
结构图
CAS No: 3027761-24-3
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MR22 is a potent pan-SIK (salt-inducible kinase) inhibitor. MR22 no longer exhibits activity on STE group kinases and displays excellent selectivity in a representative kinase panel. MR22-dependent SIK inhibition led to centrosome dissociation and subsequent cell-cycle arrest in ovarian cancer cells.