产品
编 号:F762790
分子式:C22H16N4O2
分子量:368.39
产品类型
结构图
CAS No: 3033282-93-5
联系客服
产品详情
生物活性:
Nonsteroidal aromatase inhibitor 1 (Compound 13h) is a nonsteroidal aromatase (CYP19A1) inhibitor (IC50=0.09 nM). Nonsteroidal aromatase inhibitor 1 has potential for breast cancer research. Nonsteroidal aromatase inhibitor 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
体外研究:
Nonsteroidal aromatase inhibitor 1 (0.001 pM-100 pM; 1 h) treatment shows excellent aromatase inhibition activity.Nonsteroidal aromatase inhibitor 1 (1 μM; 48 h) treatment has no impact on MCF-10A or MDA-MB-231 growth.